Which condition is marked by high blood pressure and low potassium levels?

Primary hyperaldosteronism, also known as Conn's syndrome, is characterized by high blood pressure (hypertension) and low potassium levels (hypokalemia) due to excessive secretion of the hormone aldosterone from the adrenal glands. Aldosterone plays a critical role in regulating sodium and potassium levels in the body; when it is produced in excess, it leads to increased sodium reabsorption and water retention in the kidneys, resulting in elevated blood pressure. Concurrently, the increased renal excretion of potassium leads to low potassium levels.

This condition frequently leads to and is associated with secondary hypertension, which is resistant to usual antihypertensive treatments. Identifying primary hyperaldosteronism is crucial because it can often be treated effectively, potentially reversing hypertension and minimizing related complications.

The other options represent different endocrine disorders that do not typically present with this specific combination of high blood pressure and low potassium levels. Understanding the unique presentations and pathophysiology of each condition is vital for proper diagnosis and management in the context of endocrine health.