Registered Nurse (RN) Endocrine Licensure Exam

GLP-1 receptor agonists are a class of medications that play a crucial role in the management of type 2 diabetes mellitus. The correct description indicates that these medications enhance insulin secretion specifically in the presence of elevated glucose levels. This mechanism is significant as it helps to lower blood sugar without causing hypoglycemia, making them a valuable addition to diabetes management.

GLP-1, or glucagon-like peptide-1, is an incretin hormone that promotes insulin release from pancreatic beta cells when glucose is present. By mimicking the action of this hormone, GLP-1 receptor agonists not only stimulate insulin secretion but also reduce glucagon secretion, slow gastric emptying, and promote satiety, contributing to better overall glycemic control.

In contrast, the other options do not accurately describe the role or function of GLP-1 receptor agonists. They are not antihypertensive medications, nor are they primarily used to treat conditions such as hyperlipidemia or allergies, which is why the other descriptions do not apply. Understanding this mechanism is crucial for nursing practice in diabetes care.