What hormonal disorder is associated with Addison's disease?

Addison's disease is primarily associated with adrenal insufficiency, which occurs when the adrenal glands do not produce sufficient amounts of certain hormones, particularly cortisol and sometimes aldosterone. This condition can lead to symptoms such as fatigue, weight loss, low blood pressure, and darkening of the skin.

In contrast, Cushing's syndrome involves excess cortisol production, which is the opposite of what occurs in Addison's disease. Type 1 diabetes is characterized by insufficient insulin production due to autoimmune destruction of the insulin-producing beta cells in the pancreas, while Graves' disease is an autoimmune condition leading to hyperthyroidism, resulting in excess thyroid hormone production. Neither of these last two conditions is directly related to the adrenal hormone deficiency seen in Addison's disease. Thus, adrenal insufficiency is the most relevant disorder associated with Addison's disease.